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Case Reports
. 2013 Jan;28(1):160-3.
doi: 10.3346/jkms.2013.28.1.160. Epub 2013 Jan 8.

A case of congenital infantile fibrosarcoma of sigmoid colon manifesting as pneumoperitoneum in a newborn

Hae Young Kim  1 , Yong Hoon Cho, Shin Yun Byun, Kyung Hee Park
Affiliations
Case Reports

A case of congenital infantile fibrosarcoma of sigmoid colon manifesting as pneumoperitoneum in a newborn

Hae Young Kim et al. J Korean Med Sci. 2013 Jan.

Abstract

Congenital infantile fibrosarcoma (CIF) is a rare soft-tissue tumor in the pediatric age group and seldom involves the gastrointestinal tract. A 2-day-old boy was transferred to our hospital with a pneumpoperitoneum. After emergency operation, we could find a solid mass wrapping around a sigmoid colon and performed a segmental resection of sigmoid colon including a mass. Histopathologic examination showed an infantile fibrosarcoma origining from the muscular layer of colon. The baby was discharged on the 17th hospital day and followed for 1 yr without recurrence.

Keywords: Congenital Infantile Fibrosarcoma (CIF); Gastrointestinal.

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Figures

Fig. 1
Fig. 1
Infantography shows a large amount of free-air in peritoneal cavity before operation.
Fig. 2
Fig. 2
Grossly it shows a round mass wrapping around a sigmoid colon.
Fig. 3
Fig. 3
A hypercellular and poorly circumscribed tumor mass in submucosa and muscularis proper (H&E stain, × 40), atypical spindle cells forming fascicular arrangement with mitoses and small amount of interstitial collagen in inlet (H&E stain, × 400).
Fig. 4
Fig. 4
Immunohistochemical stains of tumor cells. Positive for vimentin and smmoth muscle actin (SMA, × 200) in A, Ki-67 proliferation index 20% in B, negative for desmin (desmin, × 200) and h-caldesmon (h-caldesmon, × 200) in C, D.
Fig. 5
Fig. 5
Follow-up PET-CT shows no abnormal uptakes, evidence of tumor recurrence, 12 months later after operation.
See this image and copyright information in PMC

References

    1. Chung EB, Enzinger FM. Infantile fibrosarcoma. Cancer. 1976;38:729–739. - PubMed
    1. Moore SW, Satge D, Sasco AJ, Zimmermann A, Plaschkes J. The epidemiology of neonatal tumors. Reports of an ineternational working group. Pediatr Surg Int. 2003;19:509–519. - PubMed
    1. Grosfeld JL, Molinari F, Chaet M, Enqum SA, West KW, Rescorla FJ, Scherer LR., 3rd Gastrointestinal perforation and peritonitis in infants and children: experience with 179 cases over ten years. Surgery. 1996;120:650–656. - PubMed
    1. Khan TR, Rawat JD, Ahmed I, Rashid KA, Maletha M, Wakhlu A, Kureel SN. Neonatal pneumoperitoneum: a critical appraisal of its causes and subsequent management from a developing country. Pediatr Surg Int. 2009;25:1093–1097. - PubMed
    1. Stout AP. Fibrosarcoma in infants and children. Cancer. 1962;15:1028–1040. - PubMed

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