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. 2012 Dec;9(4):389-400.
doi: 10.3724/SP.J.1263.2012.05281.

Past and present of cardiocirculatory assist devices: a comprehensive critical review

Gianluca Rigatelli  1 , Francesco Santini, Giuseppe Faggian
Affiliations

Past and present of cardiocirculatory assist devices: a comprehensive critical review

Gianluca Rigatelli et al. J Geriatr Cardiol. 2012 Dec.

Abstract

During the last 20 years, the management of heart failure has significantly improved by means of new pharmacotherapies, more timely invasive treatments and device assisted therapies. Indeed, advances in mechanical support, namely with the development of more efficient left ventricular assist devices (LVADs), and the total artificial heart have reduced mortality and morbidity in patients awaiting transplantation, so much so, that LVADs are now approved of as a strategy for destination therapy. In this review, the authors describe in detail the current basic indications, functioning modalities, main limitations of surgical LAVDs, total artificial heart development, and percutaneous assist devices, trying to clarify this complex, but fascinating topic.

Keywords: Cardiac surgery; Cardiocirculatory support; Devices; Heart failure; Heart transplant.

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Figures

Figure 1.
Figure 1.. Futuristic totally percutaneous implantable permanent left ventricle assist device (virtual technology design).
(A): Battery in subclavian pocket; (B): Pump; (C): Interatrial septal approach.
See this image and copyright information in PMC

References

    1. Stewart S, MacIntyre K, Hole DJ, et al. More ‘malignant’ than cancer? Five-year survival following a first admission for heart failure. Eur J Heart Fail. 2001;3:315–322. - PubMed
    1. Klotz S, Loeher A, Drees G, et al. Surgical therapy of endstage heart failure. State of the art 2006. Herz. 2006;31:445–454. - PubMed
    1. Allen LA, Felker GM. Advances in the surgical treatment of heart failure. Curr Opin Cardiol. 2008;23:249–253. - PMC - PubMed
    1. Swedberg K, Kjekshus J. Effects of enalapril on mortality in severe congestive heart failure: results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS) Am J Cardiol. 1988;62:60A–66A. - PubMed
    1. Domanski MJ, Krause-Steinrauf H, Massie BM, et al. A comparative analysis of the results from 4 trials of beta-blocker therapy for heart failure: BEST, CIBIS-II, MERIT-HF, and COPERNICUS. J Card Fail. 2003;9:354–363. - PubMed