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. 2013 Jun;27(6):1938-44.
doi: 10.1007/s00464-012-2691-8. Epub 2013 Jan 24.

Thoracoscopic lung metastasectomies: a 10-year, single-center experience

Felice Lo Faso  1 , Luciano Solaini, Rosalba Lembo, Paolo Bagioni, Silvia Zago, Paolo Soliani, Robert D Pascotto
Affiliations

Thoracoscopic lung metastasectomies: a 10-year, single-center experience

Felice Lo Faso et al. Surg Endosc. 2013 Jun.

Abstract

Introduction: The ideal surgical treatment for pulmonary metastasectomy remains controversial. Minimally invasive surgery may offer advantages for quality of life outcomes, with equivalent oncologic long-term results. The purpose of our study was to confirm the validity of the thoracoscopic approach for pulmonary metastasectomy.

Methods: We retrospectively reviewed 164 patients who underwent 212 lung metastasectomies from January 2000 to December 2010. Complete curative pulmonary resections were performed in 159 (96.95 %) cases; 126 patients developed lung metastases from epithelial tumors: 28 from sarcoma, 7 from melanoma, and 3 from germ cell tumors. The mean disease-free interval (DFI) was 38.75 months. Fifty-four patients underwent a major VATS resection (53 thoracoscopic lobectomies and 1 pneumonectomy), and 110 patients underwent a wedge resection/segmentectomy. Lymph node sampling was performed in 117 cases.

Results: After a mean follow-up of 38 months, 87 patients (53 %) had died. All resection margins were tumor-free at final pathological examination. Multivariate analysis not confirmed in our series a better prognosis for patients with a particular histologic type and also DFI, age, number of metastases, and type of surgery did not statistically influence long-term survival.

Conclusions: Thoracoscopic surgery is an acceptable procedure, safe and efficacious, with a 5-year overall survival that is equivalent to open surgery.

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Figures

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Patients survival
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Completeness of resection
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Histology
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Disease Free Interval
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Nodal Status
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Epithelial tumors
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Number of metastasectomies
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Number of surgeries
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Surgery
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References

    1. Kaifi JT, Gusani NJ, Deshaies I, Kimchi ET, Reed MF, Mahraj RP, Staveley-O’Carroll KF. Indications and approach to surgical resection of lung metastases. J Surg Oncol. 2010;102(2):187–195. doi: 10.1002/jso.21596. - DOI - PubMed
    1. Pastorino U, Buyse M, Friedel G. Long-term results of lung metastasectomy: prognostic analysis based on 5206 cases. J Thoracic Cardiovasc Surg. 1997;113:37–49. doi: 10.1016/S0022-5223(97)70397-0. - DOI - PubMed
    1. Cerfolio RJ, McCarty T, Bryant AS. Non-imaged pulmonary nodules discovered during thoracotomy for metastasectomy by lung palpation. Eur J Cardiothoracic Surg. 2009;35:786–791. doi: 10.1016/j.ejcts.2009.01.012. - DOI - PubMed
    1. McCormack PM, Bains MS, Begg CB, Burt ME, Downey RJ, Panicek DM, Rusch VW, Zakowski M, Ginsberg RJ. Role of Video-assisted thoracic surgery in the treatment of pulmonary metastases: results of a prospective trial. Ann Thorac Surg. 1996;62:213–217. doi: 10.1016/0003-4975(96)00253-6. - DOI - PubMed
    1. Parsons AM, Ennis EK, Yankaskas BC, Parker LA, Jr, Hyslop WB, Detterbeck FC. Helical computed tomography inaccuracy in the detection of pulmonary metastases: can it improved? Ann Thorac Surg. 2007;84:1830–1836. doi: 10.1016/j.athoracsur.2007.06.069. - DOI - PubMed

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