Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2013 Jan 22:2013:bcr2012008153.
doi: 10.1136/bcr-2012-008153.

Pseudomembranous colitis due to Clostridium difficile as a cause of perineal necrotising fasciitis

Thibault Duburcq  1 , Erika Parmentier-Decrucq, Julien Poissy, Daniel Mathieu
Affiliations
Case Reports

Pseudomembranous colitis due to Clostridium difficile as a cause of perineal necrotising fasciitis

Thibault Duburcq et al. BMJ Case Rep. .

Abstract

Although rare, pseudomembranous colitis may be a cause of perineal necrotising fasciitis in a context of immunosuppression, as in the case we report. This origin must be quickly identified because the therapeutic management, especially surgery, is unlikely to be the same as usual. Similarly, antibiotic treatment is also a matter of discussion due to the potential deleterious role of antibiotics in pseudomembranous colitis.

PubMed Disclaimer

Figures

Figure 1
Figure 1
CT scan of pelvis performed on admission showed extensive perineal fasciitis.
Figure 2
Figure 2
CT scan performed on day 21 found an unchanged aspect of colitis.
Figure 3
Figure 3
Local aspect on day 21.
See this image and copyright information in PMC

References

    1. Libby DB, Bearman G. Bacteremia due to Clostridium difficile—review of the literature. Int J Infect Dis 2009;13:e305–9 - PubMed
    1. Ray P, Das A, Singh K, et al. Clostridium tertium in necrotizing fasciitis and gangrene. Emerg Infect Dis 2003;9:1347–9 - PMC - PubMed
    1. Kyne L, Warny M, Qamar A, et al. Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A. N Engl J Med 2000;342:390–7 - PubMed
    1. Warny M, Vaerman JP, Avesani V, et al. Human antibody response to Clostridium difficile toxin A in relation to clinical course of infection. Infect Immun 1994;62:384–9 - PMC - PubMed
    1. Green RJ, Dafoe DC, Raffin TA. Necrotizing fasciitis. Chest 1996;110:219–29 - PubMed

Publication types