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. 1999 Mar;25(1):1-22.
doi: 10.1023/A:1005159215657.

Models of assembly and disassembly of individual microtubules: stochastic and averaged equations

H Bolterauer  1 , H J Limbach, J A Tuszyński
Affiliations

Models of assembly and disassembly of individual microtubules: stochastic and averaged equations

H Bolterauer et al. J Biol Phys. 1999 Mar.

Abstract

In this paper we present solutions of the master equations for the microtubule length and show that the local probability for rescues or catastrophes can lead to bell-shaped length histograms. Conversely, as already known, non-local probabilities for these events result in exponential length histograms. We also derive master equations for a stabilizing cap and obtain a new boundary condition which provides an explanation of the results obtained in dilution and cutting experiments.

Keywords: Dynamic instability; Master equations; Microtubules.

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References

    1. Amos, L.A.: The microtubule lattice - 20 years on, Trends in Cell Biol.48 (1995). - PubMed
    1. Atkins P.W. Physical chemistry. Oxford: Oxford University Press; 1990.
    1. Bayley P.M. What makes microtubules dynamic? J. Cell Sci. 1990;95:329–334. - PubMed
    1. Bayley P.M., Martin S.R., Sharma K.K. AIP Conf. Proc. 1991;226:187–199.
    1. Belmont L.D., Hyman A.A., Sawin K.E., Mitchison T.J. Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmatic extracts. Cell. 1990;62:579–589. - PubMed