Cold and warm denaturation of proteins
- PMID: 23345746
- PMCID: PMC3456582
- DOI: 10.1023/A:1013145009949
Cold and warm denaturation of proteins
Abstract
We introduce a simplified protein model where the water degrees of freedom appear explicitly (although in an extremely simplified fashion). Using thismodel we are able to recover both the warm and the cold protein denaturation within a single framework, while addressing important issues about the structure of model proteins.
Keywords: Cold denaturation; hydrophobic forces; proteins.
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