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Case Reports
. 2012 Dec;52(6):561-3.
doi: 10.3340/jkns.2012.52.6.561. Epub 2012 Dec 31.

Desmoplastic fibroma of the cranium in a young man

Sungjoon Lee  1 , Sung-Mook Jung, Byung-Kyu Cho, Hoon Kim
Affiliations
Case Reports

Desmoplastic fibroma of the cranium in a young man

Sungjoon Lee et al. J Korean Neurosurg Soc. 2012 Dec.

Abstract

Desmoplastic fibroma, which develops predominantly in long bones and the mandible, is a rare and benign but locally aggressive tumor. Desmoplastic fibroma of the cranium is extremely rare. We report a case of desmoplastic fibroma of the frontal bone in a young man. Because of its locally aggressive behavior, complete surgical excision with a safety margin is essential.

Keywords: Desmoplastic fibroma; Frontal bone; Skull.

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Figures

Fig. 1
Fig. 1
A : CT scan demonstrating focal calvarial thickening of right frontal skull. B, C and D : MRI reveals intermediate signal intensity on T1-weighted images and heterogeneous intensity on T2-weighted images with multifocal enhancement.
Fig. 2
Fig. 2
A : Micrograph of the lesion showing spindle cell proliferation with hemorrhage and fat necrosis (H&E, ×100). B : Note fibroblastic proliferation with collagenous background (H&E, ×200). C : Smooth muscle actin staining revealed focal positivity (×200).
See this image and copyright information in PMC

References

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