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Comment
. 2013 Jan 24:11:19.
doi: 10.1186/1741-7015-11-19.

Sleeping well

Mithu Sen  1 , G Bryan Young
Affiliations
Comment

Sleeping well

Mithu Sen et al. BMC Med. .

Abstract

In a study by Cruse et al. published in BMC Medicine, patients with severe brain damage who were in the Vegetative or Minimally Conscious States (VS or MCS, respectively) from traumatic and nontraumatic etiologies had assessments of circadian rhythms using an actigraph, a device worn on a limb to evaluate circadian rhythmicity, in this population. This is a novel approach and is being used as a surrogate for polysomnography and other reference standards. Cruse et al. showed more disruption in circadian rhythms in the VS when compared to the MCS. This suggests that more brain injury occurs in the areas that control circadian rhythmicity in VS than in MCS patients. The study provides opportunities for improved prognostication and rehabilitation strategies in this patient population.

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References

    1. Cruse D, Thibaut A, Demertzi A, Nantes JC, Bruno M-A, Gosseries O, Vanhaudenhuyse A, Nekinschtein TA, Owen AM, Laureys S. Actigraphy assessments of circadian sleep-wake cycles in the vegetative and minimally conscious states. BMC Med. in press . - PMC - PubMed
    1. Jean-Louis G, von Gizycki H, Zizi F, Spielman A, Hauri P, Taub H. The actigraph data analysis software: I A novel approach to scoring and interpreting sleep-wake activity. Percept Mot Skills. 1997;85:207–216. doi: 10.2466/pms.1997.85.1.207. - DOI - PubMed
    1. Morgenthaler T, Alessi C, Friedman L, Owens J, Kapur V, Boehlecke B, Brown T, Chesson A Jr, Coleman J, Lee-Chiong T, Pancer J, Swick TJ. Practice parameters for the use of actigraphy in the assessment of sleep and sleep disorders: an update for 2007. Sleep. 2007;30:519–529. - PubMed
    1. Schiff ND. Central thalamic contributions to arousal regulation and neurological disorders of consciousness. Ann N Y Acad Sci. 2008;1129:105–118. doi: 10.1196/annals.1417.029. - DOI - PubMed
    1. Fernandez-Espejo D, Junque C, Bernabeu M, Roig-Rovira T, Vendrell P, Mercader JM. Reductions in thalamic volume and regional shape changes in the vegetative and the minimally conscious states. J Neurotrauma. 2010;27:1187–1193. doi: 10.1089/neu.2010.1297. - DOI - PubMed