[Role of serotonin receptors in the amygdaloid complex and central gray substance in conditioned passive avoidance reaction in rats]
- PMID: 2334791
[Role of serotonin receptors in the amygdaloid complex and central gray substance in conditioned passive avoidance reaction in rats]
Abstract
The functional role of 5-HT1 receptors in the memory trace retrieval was investigated in amygdala (AM), central gray substance of midbrain (CGS) and frontal cortex. There is used the passive avoidance response in the rat. The decrease of 5-HT1 binding sites in AM and CGS was revealed for the rats with retention of the passive avoidance response. The binding of 3H-5-HT in AM was found two sets of binding sites. It was concluded, that 5-HT1 receptors of AM and CGS are involved in learning processes either in the moment of the memory trace retrieval or immediately after it.
Similar articles
-
[5-HT1 receptors in rats with amnesia].Biull Eksp Biol Med. 1989 Jul;108(7):51-2. Biull Eksp Biol Med. 1989. PMID: 2804300 Russian.
-
[Changes in brain serotonin metabolism and [3H]-serotonin receptor binding during recall of conditioned passive avoidance in rats].Zh Vyssh Nerv Deiat Im I P Pavlova. 2004 Jul-Aug;54(4):533-41. Zh Vyssh Nerv Deiat Im I P Pavlova. 2004. PMID: 15481391 Russian.
-
Serotonergic mechanisms of memory trace retrieval.Behav Brain Res. 2008 Dec 16;195(1):7-16. doi: 10.1016/j.bbr.2007.12.005. Epub 2008 Feb 19. Behav Brain Res. 2008. PMID: 18243361 Review.
-
[The pre- and postsynaptic mechanisms of the involvement of the serotonin of the amygdaloid body in the reproduction of the conditioned passive avoidance reaction in rats].Zh Vyssh Nerv Deiat Im I P Pavlova. 1998 May-Jun;48(3):464-70. Zh Vyssh Nerv Deiat Im I P Pavlova. 1998. PMID: 9700910 Russian.
-
Central serotonergic receptors: evidence for heterogeneity and characterization by ligand-binding.Neurosci Biobehav Rev. 1982 Winter;6(4):499-502. doi: 10.1016/0149-7634(82)90031-8. Neurosci Biobehav Rev. 1982. PMID: 6757812 Review.