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. 2013 Aug;14(8):768-74.
doi: 10.1016/j.sleep.2012.09.026. Epub 2013 Jan 21.

Rapid eye movement sleep behavior disorder in adults younger than 50 years of age

Yo-El S Ju  1
Affiliations

Rapid eye movement sleep behavior disorder in adults younger than 50 years of age

Yo-El S Ju. Sleep Med. 2013 Aug.

Abstract

Rapid eye movement (REM) sleep behavior disorder (RBD) occurring prior to age 50 is termed early-onset RBD. Early-onset RBD comprises a substantial minority of cases, and demonstrates the differences in demographics, comorbidities, and clinical considerations from previously described typical RBD with onset >50years. The world literature on RBD is reviewed with specific focus on features that distinguish early-onset RBD, including more gender parity, increased proportion of idiopathic cases, increased proportion of cases associated with narcolepsy, parasomnia overlap disorder, antidepressants, and possibly autoimmune disorders, and clinical presentation.

Keywords: Antidepressant; Autoimmune; Narcolepsy; Parasomnia; Parasomnia overlap disorder (POD); REM sleep behavior disorder (RBD).

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Conflict of interest statement

Conflict of Interest

The ICMJE Uniform Disclosure Form for Potential Conflicts of Interest associated with this article can be viewed by clicking on the following link: http://dx.doi.org/10.1016/j.sleep.2012.09.026.

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