Acute stroke in a patient with advanced uraemia: should thrombolysis be given?
- PMID: 23355564
- PMCID: PMC3604296
- DOI: 10.1136/bcr-2012-007307
Acute stroke in a patient with advanced uraemia: should thrombolysis be given?
Abstract
A 65-year-old gentleman with stage 5 chronic kidney disease developed an acute posterior circulation stroke, which was treated with intravenous thrombolytic therapy. This was complicated by a retroperitoneal haemorrhage. The patient made an excellent neurological recovery and was discharged to home, independently mobile, having been established on haemodialysis. This case highlights the challenges of managing acute ischaemic stroke in patients with advanced uraemia.
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References
-
- Khella S, Bleicher MB. Stroke and its prevention in chronic kidney disease. Clin J Am Soc Nephrol 2007;2:1343–51 - PubMed
-
- Seliger SL, Gillen DL, Tirschwell D, et al. Risk factors for incident stroke among patients with end-stage renal disease. J Am Soc Nephrol 2003;14:2623–31 - PubMed
-
- Seliger SL, Gillen DL, Longstreth WT, Jr, et al. Elevated risk of stroke among patients with end-stage renal disease. Kidney Int 2003;64:603–9 - PubMed
-
- Hedges SJ, Dehoney SB, Hooper JS, et al. Evidence-based treatment recommendations for uraemic bleeding. Nat Clin Pract Nephrol 2007;3:138–53 - PubMed
-
- De Keyser J, Gdovinova Z, Uyttenboogaart M, et al. Intravenous alteplase for stroke: beyond the guidelines and in particular clinical situations. Stroke 2007;38:2612–8 - PubMed
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