The burden of faulty proofreading in colon cancer
- PMID: 23358219
- DOI: 10.1038/ng.2540
The burden of faulty proofreading in colon cancer
Erratum in
- Nat Genet. 2013 Oct;45(10):1261
Abstract
Our understanding of inherited risk factors for colorectal cancer (CRC) is incomplete. A new study reports the identification of germline CRC risk variants that adversely affect the proofreading function of DNA polymerases encoded by POLE and POLD1.
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