Insulin resistance and glucose and lipid concentrations in a cohort of perinatally HIV-infected Latin American children
- PMID: 23360832
- PMCID: PMC3695016
- DOI: 10.1097/INF.0b013e318286c774
Insulin resistance and glucose and lipid concentrations in a cohort of perinatally HIV-infected Latin American children
Abstract
We measured glucose, insulin and lipids in 249 perinatally HIV-infected Latin American children. Only 1 subject had impaired fasting glucose; 6.8% had insulin resistance. Abnormalities in total, low-density lipoprotein and high-density lipoprotein cholesterol and triglycerides were reported for 13%, 13%, 21% and 34%, respectively. Continued follow-up of this population is necessary to characterize the evolution and clinical consequences of these findings.
Conflict of interest statement
The authors have no conflicts of interest to disclose.
References
-
- Hazra R, Siberry GK, Mofenson LM. Growing up with HIV: children, adolescents, and young adults with perinatally acquired HIV infection. Annual Review of Medicine. 2010;61:169–85. - PubMed
-
- Beregszaszi M, Dollfus C, Levine M, Faye A, Deghmoun S, Bellal N, et al. Longitudinal evaluation and risk factors of lipodystrophy and associated metabolic changes in HIV-infected children. J Acquir Immune Defic Syndr. 2005;40(2):161–8. - PubMed
-
- Amaya RA, Kozinetz CA, McMeans A, Schwarzwald H, Kline MW. Lipodystrophy syndrome in human immunodeficiency virus-infected children. The Pediatric Infectious Disease Journal. 2002;21(5):405–10. - PubMed
-
- Rosso R, Parodi A, d'Annunzio G, Ginocchio F, Nicolini L, Torrisi C, et al. Evaluation of insulin resistance in a cohort of HIV-infected youth. European journal of endocrinology / European Federation of Endocrine Societies. 2007;157(5):655–9. - PubMed
-
- Lee B, Aurpibul L, Sirisanthana V, Mangklabruks A, Sirisanthana T, Puthanakit T. Low prevalence of insulin resistance among HIV-infected children receiving nonnucleoside reverse transcriptase inhibitor-based highly active antiretroviral therapy in Thailand. HIV Medicine. 2009;10(2):72–8. - PubMed
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