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Comment
. 2013 Feb;10(2):117-8.
doi: 10.1038/nmeth.2338.

A third-generation method reveals cell lineage ancestry

Andrew P Feinberg  1
Affiliations
Comment

A third-generation method reveals cell lineage ancestry

Andrew P Feinberg. Nat Methods. 2013 Feb.

Abstract

A combination of proximity ligation and in situ hybridization enables visualization of epigenetic marks in single cells.

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Conflict of interest statement

COMPETING FINANCIAL INTERESTS

The author declares no competing financial interests.

Figures

Figure 1
Figure 1
ISH-PLA and one of many potential applications. (a) General scheme of ISH-PLA. (b) A possible application includes a dual-color ISH-PLA for two chromatin marks. Users could then test for cellular heterogeneity of epigenetic marks (yellow and red dots) in normal and cancer cells.
See this image and copyright information in PMC

Comment on

References

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