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. 2013 Jan 30:13:54.
doi: 10.1186/1471-2334-13-54.

An update of "Cost-effectiveness of rotavirus vaccination in the Netherlands: the results of a Consensus Rotavirus Vaccine model"

Hong Anh T Tu  1 , Mark H Rozenbaum, Pieter T de Boer, Albert C Noort, Maarten J Postma
Affiliations

An update of "Cost-effectiveness of rotavirus vaccination in the Netherlands: the results of a Consensus Rotavirus Vaccine model"

Hong Anh T Tu et al. BMC Infect Dis. .

Abstract

Background: To update a cost-effectiveness analysis of rotavirus vaccination in the Netherlands previously published in 2011.

Methods: The rotavirus burden of disease and the indirect protection of older children and young adults (herd protection) were updated.

Results: When updated data was used, routine infant rotavirus vaccination in the Netherlands would potentially become an even more cost-effective strategy than previously estimated with the incremental cost per QALY at only €3,000-4,000. Break-even total vaccination costs were indicated at €92-122, depending on the applied threshold.

Conclusions: We concluded that the results on potentially favourable cost-effectiveness in the previous study remained valid, however, the new data suggested that previous results might represent an underestimation of the economic attractiveness of rotavirus vaccination.

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References

    1. Rozenbaum MH, Mangen MJ, Giaquinto C, Wilschut JC, Hak E, Postma MJ. Cost-effectiveness of rotavirus vaccination in the Netherlands; the results of a consensus model. BMC Public Health. 2011;11:462. doi: 10.1186/1471-2458-11-462. - DOI - PMC - PubMed
    1. Bruijning-Verhagen P, de Waal W, Winkel L, Felderhof M, van Houten M, Thijsen S, Rotavirus related hospitalizations: Incidence and contribution to seasonal peaks in pediatric hospital admissions. Thessaloniki, Greece: Poster at ESPID-conference 2012; 2012.
    1. Friesema IH, De Boer RF, Duizer E, Kortbeek LM, Notermans DW, Norbruis OF. et al. Etiology of acute gastroenteritis in children requiring hospitalization in the Netherlands. Eur J Clin Microbiol Infect Dis. 2012;31:405–415. doi: 10.1007/s10096-011-1320-0. - DOI - PubMed
    1. de Wit MA, Koopmans MP, Kortbeek LM, van Leeuwen NJ, Bartelds AI, van Duynhoven YT. Gastroenteritis in sentinel general practices, The Netherlands. Emerg Infect Dis. 2001;7:82–91. doi: 10.3201/eid0701.010113. - DOI - PMC - PubMed
    1. de Wit MA, Koopmans MP, Kortbeek LM, Wannet WJ, Vinje J, van LF. et al. Sensor, a population-based cohort study on gastroenteritis in the Netherlands: incidence and etiology. Am J Epidemiol. 2001;154:666–674. doi: 10.1093/aje/154.7.666. - DOI - PubMed

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