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. 2013 Feb;17(2):148-51.
doi: 10.1007/s12603-012-0386-4.

Nutritional status in Parkinson's disease patients undergoing deep brain stimulation surgery: a pilot study

J M Sheard  1 , S Ash, P A Silburn, G K Kerr
Affiliations

Nutritional status in Parkinson's disease patients undergoing deep brain stimulation surgery: a pilot study

J M Sheard et al. J Nutr Health Aging. 2013 Feb.

Abstract

Objectives: People with Parkinson's disease (PD) are at higher risk of malnutrition due to PD symptoms and pharmacotherapy side effects. When pharmacotherapy is no longer effective for symptom control, deep-brain stimulation (DBS) surgery may be considered. The aim of this study was to assess the nutritional status of people with PD who may be at higher risk of malnutrition related to unsatisfactory symptom management with optimised medical therapy.

Design: This was an observational study using a convenience sample.

Setting: Participants were seen during their hospital admission for their deep brain stimulation surgery.

Participants: People with PD scheduled for DBS surgery were recruited from a Brisbane neurological clinic (n=15).

Measurements: The Patient-Generated Subjective Global Assessment (PG-SGA), weight, height and body composition were assessed to determine nutritional status.

Results: Six participants (40%) were classified as moderately malnourished (SGA-B). Eight participants (53%) reported previous unintentional weight loss (average loss of 13%). On average, participants classified as well-nourished (SGA-A) were younger, had shorter disease durations, lower PG-SGA scores, higher body mass (BMI) and fat free mass indices (FFMI) when compared to malnourished participants (SGA-B). Five participants had previously received dietetic advice but only one in relation to unintentional weight loss.

Conclusion: Malnutrition remains unrecognised and untreated in this group despite unintentional weight loss and presence of nutrition impact symptoms. Improving nutritional status prior to surgery may improve surgical outcomes.

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References

    1. Atlantis E., Browning C., Kendig H. Body mass index and unintentional weight change associated with all-cause mortality in older Australians: The Melbourne Longitudinal Studies on Healthy Ageing (MELSHA) Age & Ageing. 2010;39:559–565. 10.1093/ageing/afq073 - DOI - PubMed
    1. Crogan N.L., Pasvogel A. The influence of protein-calorie malnutrition on quality of life in nursing homes. J Gerontol A Biol Sci Med Sci. 2003;58:159–164. 10.1093/gerona/58.2.M159 PubMed PMID: 12586854. - DOI - PubMed
    1. Neumann S.A., Miller M.D., Daniels L., Crotty M. Nutritional status and clinical outcomes of older patients in rehabilitation. J Hum Nutr Diet. 2005;18:129–136. 10.1111/j.1365-277X.2005.00596.x PubMed PMID: 15788022. - DOI - PubMed
    1. van der Marck M.a., Dicke H.C., Uc E.Y., Kentin Z.a., Borm G.F., Bloem B.R., et al. Body mass index in Parkinson’s disease: A meta-analysis. Parkinsonism Relat Disord. 2012;18:263–267. 10.1016/j.parkreldis.2011.10.016 PubMed PMID: 22100523. - DOI - PubMed
    1. Beyer P.L., Palarino M.Y., Michalek D., Busenbark K., Koller W.C. Weight change and body composition in patients with Parkinson’s disease. J Am Diet Assoc. 1995;95:979–983. 10.1016/S0002-8223(95)00269-3 PubMed PMID: 7657912. - DOI - PubMed

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