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. 1990 Apr;8(2):101-4.
doi: 10.1016/0264-410x(90)90129-a.

Use of a vaccinia-rabies recombinant virus for the oral vaccination of foxes against rabies

B Brochier  1 , I Thomas, B Bauduin, T Leveau, P P Pastoret, B Languet, G Chappuis, P Desmettre, J Blancou, M Artois
Affiliations
Free article

Use of a vaccinia-rabies recombinant virus for the oral vaccination of foxes against rabies

B Brochier et al. Vaccine. 1990 Apr.
Free article

Abstract

The vaccination of wild animals against rabies has been developed most extensively in Europe. Experiments have demonstrated the efficacy of a vaccinia-rabies recombinant virus administered by the oral route in foxes. The innocuity of this vaccine was tested in the target species as well as in several non-target wild and domestic species. Because of its safety and heat-stability, this recombinant virus should offer an excellent alternative to the attenuated strains of rabies virus currently used in the field. A large scale field trial was conducted in Belgium in October 1988 to assess the efficacy of this new vaccine-bait systems.

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