Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2013 Feb 15;12(4):544-5.
doi: 10.4161/cc.23678. Epub 2013 Jan 31.

Sensing hyperploidy and immune surveillance: a pas-de-deux

Navin R Mahadevan  1 , Maurizio Zanetti
Affiliations
Comment

Sensing hyperploidy and immune surveillance: a pas-de-deux

Navin R Mahadevan et al. Cell Cycle. .
No abstract available

Keywords: ER stress response; calreticulin; colon cancer; cytotoxic lymphocytes; eIF2a; hyperploidy; immune surveillance; organoids; ploidy.

PubMed Disclaimer

Comment on

References

    1. Burnet FM. The concept of immunological surveillance. Prog Exp Tumor Res. 1970;13:1–27. - PubMed
    1. Boilève A, Senovilla L, Vitale I, Lissa D, Martins I, Métivier D, et al. Immunosurveillance against tetraploidization-induced colon tumorigenesis. Cell Cycle. 2013;12 In press. - PMC - PubMed
    1. Tsuiki H, Nitta M, Tada M, Inagaki M, Ushio Y, Saya H. Mechanism of hyperploid cell formation induced by microtubule inhibiting drug in glioma cell lines. Oncogene. 2001;20:420–9. doi: 10.1038/sj.onc.1204126. - DOI - PubMed
    1. Obeid M, Tesniere A, Ghiringhelli F, Fimia GM, Apetoh L, Perfettini JL, et al. Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat Med. 2007;13:54–61. doi: 10.1038/nm1523. - DOI - PubMed
    1. Walter P, Ron D. The unfolded protein response: from stress pathway to homeostatic regulation. Science. 2011;334:1081–6. doi: 10.1126/science.1209038. - DOI - PubMed

MeSH terms

Substances

LinkOut - more resources