Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2013 Feb 15;12(4):541.
doi: 10.4161/cc.23671. Epub 2013 Jan 31.

The dual nature of Notch in tissue homeostasis and carcinogenesis

Joseph M Valdez, Li Xin
Editorial

The dual nature of Notch in tissue homeostasis and carcinogenesis

Joseph M Valdez et al. Cell Cycle. .
No abstract available

Keywords: Notch; carcinogenesis; pleiotropic; stem cell; tissue homeostasis.

PubMed Disclaimer

Comment on

  • Valdez JM, Zhang L, Su Q, Dakhova O, Zhang Y, Shahi P, et al. Notch and TGFβ form a reciprocal positive regulatory loop that suppresses murine prostate basal stem/progenitor cell activity. Cell Stem Cell. 2012;11:676–88. doi: 10.1016/j.stem.2012.07.003. doi: 10.1016/j.stem.2012.07.003

References

    1. Valdez JM, Zhang L, Su Q, Dakhova O, Zhang Y, Shahi P, et al. Notch and TGFβ form a reciprocal positive regulatory loop that suppresses murine prostate basal stem/progenitor cell activity. Cell Stem Cell. 2012;11:676–88. doi: 10.1016/j.stem.2012.07.003. - DOI - PMC - PubMed
    1. Klüppel M, Wrana JL. Turning it up a Notch: cross-talk between TGF beta and Notch signaling. Bioessays. 2005;27:115–8. doi: 10.1002/bies.20187. - DOI - PubMed
    1. Nguyen B-C, Lefort K, Mandinova A, Antonini D, Devgan V, Della Gatta G, et al. Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. Genes Dev. 2006;20:1028–42. doi: 10.1101/gad.1406006. - DOI - PMC - PubMed
    1. Miele L. Transcription factor RBPJ/CSL: a genome-wide look at transcriptional regulation. Proc Natl Acad Sci U S A. 2011;108:14715–6. doi: 10.1073/pnas.1110570108. - DOI - PMC - PubMed
    1. Ranganathan P, Weaver KL, Capobianco AJ. Notch signalling in solid tumours: a little bit of everything but not all the time. Nat Rev Cancer. 2011;11:338–51. doi: 10.1038/nrc3035. - DOI - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources