Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2013 Jan 30:2013:bcr2012008315.
doi: 10.1136/bcr-2012-008315.

Survival from profound metabolic acidosis due to hypovolaemic shock. A world record?

Affiliations
Case Reports

Survival from profound metabolic acidosis due to hypovolaemic shock. A world record?

Nicola Di Rollo et al. BMJ Case Rep. .

Abstract

This case describes the unexpected survival of an adult man who presented to the emergency department with hypovolaemic shock secondary to a splenic haemorrhage. Before surgery he had a pH 6.527, base excess (BE) -34.2 mmol/l and lactate 15.6 mmol/l. He underwent a splenectomy after which his condition stabilised. He was managed in the intensive care unit postoperatively where he required organ support including renal replacement therapy but was subsequently discharged home with no neurological or renal deficit. Although there are case reports of patients surviving such profound metabolic acidosis these have mainly been cases of near drowning or toxic alcohol ingestion. To the best of our knowledge this is the first reported case of survival after a pH of 6.5 secondary to hypovolaemic shock.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Serial arterial blood gases in theatre.

References

    1. Ganong W. Review of medical physiology. 19th edn Stamford, CT: Appleton & Lange, 1999
    1. Prough DS, Bidani A. Hyperchloremic metabolic acidosis is a predictable consequence of intraoperative infusion of 0.9% saline. Anesthesiology 1999;90:1247–9 - PubMed
    1. Eisenhut M. Causes and effects of hyperchloremic acidosis. Crit Care 2006;10:413. - PMC - PubMed
    1. Kostek H, Kujawa A, Szponar J, et al. Is it possible to survive metabolic acidosis with a pH measure of below 6.8? A study of two cases of inedible alcohol intoxication. Przeglad Lekarski 2011;68:518–20 - PubMed
    1. Kujawa A, Kostek H, Szponar J, et al. Extremely severe metabolic acidosis and multi-organ complications in ethylene glycol intoxication: a case study. Przeglad Lekarski 2011;68:530–2 - PubMed

Publication types