Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Feb 4;4(1):4.
doi: 10.1186/2042-6410-4-4.

Addressing the gaps: sex differences in osteoarthritis of the knee

Barbara D Boyan  1 , Laura L Tosi, Richard D Coutts, Roger M Enoka, David A Hart, Daniel P Nicolella, Karen J Berkley, Kathleen A Sluka, C Kent Kwoh, Mary I O'Connor, Wendy M Kohrt, Eileen Resnick
Affiliations

Addressing the gaps: sex differences in osteoarthritis of the knee

Barbara D Boyan et al. Biol Sex Differ. .

Abstract

An introduction to the accompanying three papers.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Anterior (A) and lateral (B) views of a healthy knee joint showing the meniscus (a), lateral collateral ligament (b), distal femur (c), medial collateral ligament (d), posterior cruciate ligament (e), anterior cruciate ligament (f), proximal tibia (g), periosteum (i), joint capsule (j), patella (k), subchondral bone (l), and normal articular cartilage (m). Degradation of the articular cartilage due to OA is shown in C.
Figure 2
Figure 2
Prevalence of arthritis by age group for US men (blue) and women (pink) in 2003–2005 (top panel) and current and projected prevalence of arthritis for US men and women (bottom panel). The graphs are based on data from the Centers for Disease Control website.
See this image and copyright information in PMC

References

    1. Felson DT, Lawrence RC, Dieppe PA, Hirsch R, Helmick CG, Jordan JM, Kington RS, Lane NE, Nevitt MC, Zhang Y, Sowers M, McAlindon T, Spector TD, Poole AR, Yanovski SZ, Ateshian G, Sharma L, Buckwalter JA, Brandt KD, Fries JF. Osteoarthritis: new Insights. Part 1: the disease and its risk factors. Ann Intern Med. 2000;133:635–646. - PubMed
    1. Frank CB, Shrive NG, Boorman RS, Lo IKY, Hart DA. New perspectives on bioengineering of joint tissues: joint adaptation creates a moving target for engineering replacement tissues. Ann Biomed Engin. 2004;32:458–465. - PubMed
    1. Loeser RF, Goldring SR, Scanzello CR, Goldring MB. Osteoarthritis. A disease of the joint as an organ. Arthritis Rheum. 2012;64:1697–1707. doi: 10.1002/art.34453. - DOI - PMC - PubMed
    1. O’Connor MJ. Sex differences in osteoarthritis of the hip and knee. J Am Acad Orthop Surg. 2007;15:522–525. - PubMed
    1. Srikanth VK, Fryer JL, Zhai G, Winzenberg TM, Hosmer D, Jones G. A meta-analysis of sex differences prevalence, incidence and severity of osteoarthritis. Osteoarthritis Cartilage. 2005;13:769–781. doi: 10.1016/j.joca.2005.04.014. - DOI - PubMed

LinkOut - more resources