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Comparative Study
. 2013 Mar;144(1-3):146-50.
doi: 10.1016/j.schres.2012.12.012. Epub 2013 Feb 1.

Functional outcomes, functional capacity, and cognitive impairment in schizotypal personality disorder

Margaret M McClure  1 , Philip D Harvey, Christopher R Bowie, Brian Iacoviello, Larry J Siever
Affiliations
Comparative Study

Functional outcomes, functional capacity, and cognitive impairment in schizotypal personality disorder

Margaret M McClure et al. Schizophr Res. 2013 Mar.

Abstract

Background: Individuals with schizotypal personality disorder (SPD) exhibit impaired cognitive functioning in a pattern similar to that found in schizophrenia; less clear is the extent to which these individuals also share schizophrenia patients' impairments in functional capacity and real-world functioning.

Method: We evaluated 46 SPD patients, as well as 38 individuals with avoidant personality disorder (AvPD) and 55 healthy controls (HC) on: cognitive functioning, real-world functioning (employment and residential status), and functional capacity (indexed by the UPSA, a performance-based skills assessment).

Results: We found that individuals with SPD exhibited worse performance on both the cognitive battery and the UPSA than the other groups; they were also less likely to be employed and to be living independently. Additionally, cognitive and UPSA performance in the SPD group was intercorrelated to a degree comparable to what has been found in schizophrenia, and this relationship was not present in the AvPD group. Finally, real-world functioning was related to UPSA performance for both patient groups.

Conclusions: SPD patients exhibit impaired real-world functioning suggesting that these deficits extend across the schizophrenia spectrum. In addition, there is supportive evidence for the validity and importance of performance-based measures such as the UPSA to predict everyday outcomes across the schizophrenia spectrum.

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References

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