Evaluation of mutagenicity of wastewater in the vicinity of pesticide industry
- PMID: 23376178
- DOI: 10.1016/j.etap.2012.12.013
Evaluation of mutagenicity of wastewater in the vicinity of pesticide industry
Abstract
Pesticide industrial wastewater samples were taken from the Chinhat industrial area nearby Lucknow city, India. GC-MS analysis revealed the presence of pesticides lindane, α-endosulfan, β-endosulfan, chlorpyriphos, monocrotophos, dimethoate and malathion. A pesticide mixture and wastewater extracts were studied to determine the mutagenicity by Ames Salmonella test, survival of DNA repair defective E. coli K-12 mutants and bacteriophage λ systems. Wastewater samples were concentrated with XAD-resins as an adsorbent and liquid-liquid extraction procedure. The XAD concentrated sample exhibited maximum mutagenic activity in comparison to liquid-liquid extracted sample. TA98 strain was the most responsive strain for both test samples with (+S9) and without (-S9) metabolic activation, while other strains exhibited weak response. A significant decline of DNA repair defective E. coli K-12 mutants, bacteriophage λ was observed with test samples in the survival. The intracellular damage was highest when treated with XAD concentrated sample as compared to liquid-liquid extract after 6h treatment.
Copyright © 2013 Elsevier B.V. All rights reserved.
Similar articles
-
Genotoxicity of wastewaters used for irrigation of food crops.Environ Toxicol. 2009 Apr;24(2):103-15. doi: 10.1002/tox.20389. Environ Toxicol. 2009. PMID: 18442071
-
Genotoxicity assessments of alluvial soil irrigated with wastewater from a pesticide manufacturing industry.Environ Monit Assess. 2015 Oct;187(10):638. doi: 10.1007/s10661-015-4830-x. Epub 2015 Sep 22. Environ Monit Assess. 2015. PMID: 26394621
-
Genotoxicity of agricultural soils in the vicinity of industrial area.Mutat Res. 2009 Mar 17;673(2):124-32. doi: 10.1016/j.mrgentox.2008.12.006. Epub 2009 Jan 9. Mutat Res. 2009. PMID: 19167512
-
Genotoxic activity and potency of 135 compounds in the Ames reversion test and in a bacterial DNA-repair test.Mutat Res. 1984 May;133(3):161-98. doi: 10.1016/0165-1110(84)90016-2. Mutat Res. 1984. PMID: 6374443 Review.
-
Mutagenic potential of medicinal plants evaluated by the Ames Salmonella/microsome assay: A systematic review.Mutat Res Rev Mutat Res. 2020 Oct-Dec;786:108338. doi: 10.1016/j.mrrev.2020.108338. Epub 2020 Oct 18. Mutat Res Rev Mutat Res. 2020. PMID: 33339578
Cited by
-
A Review on Environmental Contaminants-Related Fertility Threat in Male Fishes: Effects and Possible Mechanisms of Action Learned from Wildlife and Laboratory Studies.Animals (Basel). 2021 Sep 27;11(10):2817. doi: 10.3390/ani11102817. Animals (Basel). 2021. PMID: 34679838 Free PMC article. Review.
-
Monocrotophos pesticide affects synthesis and conversion of sex steroids through multiple targets in male goldfish (Carassius auratus).Sci Rep. 2017 May 23;7(1):2306. doi: 10.1038/s41598-017-01935-6. Sci Rep. 2017. PMID: 28536437 Free PMC article.
-
Cyto-genotoxic potential of petroleum refinery wastewater mixed with domestic sewage used for irrigation of food crops in the vicinity of an oil refinery.Heliyon. 2021 Oct 6;7(10):e08116. doi: 10.1016/j.heliyon.2021.e08116. eCollection 2021 Oct. Heliyon. 2021. PMID: 34693051 Free PMC article.
-
Mutagenicity, genotoxicity and oxidative stress induced by pesticide industry wastewater using bacterial and plant bioassays.Biotechnol Rep (Amst). 2019 Oct 24;24:e00389. doi: 10.1016/j.btre.2019.e00389. eCollection 2019 Dec. Biotechnol Rep (Amst). 2019. PMID: 31763201 Free PMC article.
-
Monocrotophos pesticide decreases the plasma levels of total 3,3',5-triiodo-l-thyronine and alters the expression of genes associated with the thyroidal axis in female goldfish (Carassius auratus).PLoS One. 2014 Sep 30;9(9):e108972. doi: 10.1371/journal.pone.0108972. eCollection 2014. PLoS One. 2014. PMID: 25268935 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Miscellaneous
