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Case Reports
. 2012 Oct-Dec;10(4):502-4.
doi: 10.1590/s1679-45082012000400018.

Not all that shines is cancer: pulmonary cryptococcosis mimicking lymphoma in [(18)] F fluoro-2-deoxy-D-glucose positron emission tomography

[Article in English, Portuguese]
Nelson Hamerschlak  1 , Jacyr Pasternak, Jairo Wagner, Guilherme Fleury Perini
Affiliations
Free article
Case Reports

Not all that shines is cancer: pulmonary cryptococcosis mimicking lymphoma in [(18)] F fluoro-2-deoxy-D-glucose positron emission tomography

[Article in English, Portuguese]
Nelson Hamerschlak et al. Einstein (Sao Paulo). 2012 Oct-Dec.
Free article

Abstract

We report of a case of pulmonary cryptococcosis mimicking lymphoma in a positron emission tomography (FDG-PET) scan. A 62-year old man with diffuse large B-cell lymphoma had complete resolution of abdominal and pulmonary lesions after three cycles of rituximab-based chemotherapy (R-CHOP). However, FDG-PET showed new pulmonary nodules, suggesting active lymphoma. Chronic inflammatory granuloma was seen in the histopathological exam, with round-shaped structures compatible with fungus, later identified as Cryptococcus neoformans on culture. The lesions disappeared after 6 weeks of fluconazole therapy, and the patient could continue chemotherapy without further infectious complications.

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