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Review
. 2013:9:37-45.
doi: 10.2147/VHRM.S30378. Epub 2013 Jan 29.

Metabolic biomarkers for predicting cardiovascular disease

Affiliations
Review

Metabolic biomarkers for predicting cardiovascular disease

Jana E Montgomery et al. Vasc Health Risk Manag. 2013.

Abstract

Cardiac and peripheral vascular biomarkers are increasingly becoming targets of both research and clinical practice. As of 2008, cardiovascular-related medical care accounts for greater than 20% of all the economic costs of illness in the United States. In the age of burgeoning financial pressures on the entire health care system, never has it been more important to try to understand who is at risk for cardiovascular disease in order to prevent new events. In this paper, we will discuss the cost of cardiovascular disease to society, clarify the definition of and need for biomarkers, offer an example of a current biomarker, namely high-sensitivity C-reactive protein, and finally examine the approval process for utilizing these in clinical practice.

Keywords: cardiac biomarkers; cardiovascular disease.

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Figures

Figure 1
Figure 1
Total economic cost of the leading diagnostic groups in the US, 2008. Copyright © 2011. Reproduced with permission from the National Heart, Lung, and Blood Institute; National Institutes of Health; US Department of Health and Human Services. Available from: http://www.nhlbi.nih.gov/about/factbook/FactBook2011.pdf.

References

    1. Mensah GA, Brown DW. An overview of cardiovascular disease burden in the United States. Health Aff (Millwood) 2007;26(1):38–48. - PubMed
    1. Lloyd-Jones DM, Larson MG, Beiser A, Levy D. Lifetime risk of developing coronary heart disease. Lancet. 1999;353(9147):89–92. - PubMed
    1. National Heart L, and Blood Institute. FY 2011 Fact Book. 2011. [Accessed August 24, 2012]. Available from: http://www.nhlbi.nih.gov/about/factbook/FactBook2011.pdf.
    1. Hlatky MA, Greenland P, Arnett DK, et al. Criteria for evaluation of novel markers of cardiovascular risk: a scientific statement from the American Heart Association. Circulation. 2009;119(17):2408–2416. - PMC - PubMed
    1. Vasan RS. Biomarkers of cardiovascular disease: molecular basis and practical considerations. Circulation. 2006;113(19):2335–2362. - PubMed