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. 2013 Apr;51(4):1294-7.
doi: 10.1128/JCM.00058-13. Epub 2013 Feb 6.

Changes in Streptococcus pneumoniae serotype 19A invasive infections in children from 1993 to 2011

Kristina G Hulten  1 , Sheldon L Kaplan, Linda B Lamberth, William J Barson, José R Romero, Philana Ling Lin, John S Bradley, Laurence B Givner, Tina Q Tan, Jill A Hoffman, Edward O Mason
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Changes in Streptococcus pneumoniae serotype 19A invasive infections in children from 1993 to 2011

Kristina G Hulten et al. J Clin Microbiol. 2013 Apr.

Abstract

Among 594 Streptococcus pneumoniae serotype 19A invasive pneumococcal disease (IPD) isolates collected from 1993 to 2011, we identified 85 sequence types by multilocus sequence typing. CC320 was associated with multidrug resistance and reduced susceptibility to penicillin and ceftriaxone and still predominated among declining serotype 19A IPD isolates following PCV13 introduction.

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Figures

Fig 1
Fig 1
Number of serotype 19A isolates per year for the period 1993 to 2011, in total and for the most common clonal clusters. The introductions of pneumococcal conjugate vaccines PCV7 and PCV13 are indicated.
Fig 2
Fig 2
eBURST of 594 serotype 19A IPD isolates obtained from 1993 to 2011.
See this image and copyright information in PMC

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