Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2013 Feb 7;49(3):423-5.
doi: 10.1016/j.molcel.2013.01.027.

Activation and degradation of mitofusins: two pathways regulate mitochondrial fusion by reversible ubiquitylation

Nils Wiedemann  1 , Sebastian B Stiller, Nikolaus Pfanner
Affiliations
Free article
Comment

Activation and degradation of mitofusins: two pathways regulate mitochondrial fusion by reversible ubiquitylation

Nils Wiedemann et al. Mol Cell. .
Free article

Abstract

Mitofusins are large GTPases essential for mitochondrial fusion. In this issue, Anton et al. (2013) report that two independent pathways of ubiquitylation/deubiquitylation control activation and degradation of mitofusins, revealing a sophisticated mechanism of regulating mitochondrial dynamics.

PubMed Disclaimer

Comment on

LinkOut - more resources