A "complex" issue: deciphering the role of variant PRC1 in ESCs
- PMID: 23395440
- DOI: 10.1016/j.stem.2013.01.014
A "complex" issue: deciphering the role of variant PRC1 in ESCs
Abstract
Several noncanonical type-1 Polycomb Repressive Complexes (PRC1) that act independently of PRC2 have been recently identified, but their functions in embryonic stem cells (ESCs) are unclear. Two recent reports by Morey et al. (2012a) and Wu et al. (2013) define functionally distinct roles for canonical and noncanonical PRC1 in ESCs.
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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RYBP and Cbx7 define specific biological functions of polycomb complexes in mouse embryonic stem cells.Cell Rep. 2013 Jan 31;3(1):60-9. doi: 10.1016/j.celrep.2012.11.026. Epub 2012 Dec 27. Cell Rep. 2013. PMID: 23273917
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