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. 2013 Feb 8:2013:bas058.
doi: 10.1093/database/bas058. Print 2013.

'What's in the NIDDK CDR?'--public query tools for the NIDDK central data repository

Huaqin Pan  1 , Mary-Anne Ardini, Vesselina Bakalov, Michael DeLatte, Paul Eggers, Laxminarayana Ganapathi, Craig R Hollingsworth, Joshua Levy, Sheping Li, Joseph Pratt, Norma Pugh, Ying Qin, Rebekah Rasooly, Helen Ray, Jean E Richardson, Amanda Flynn Riley, Susan M Rogers, Sylvia Tan, Charles F Turner, Stacie White, Philip C Cooley
Affiliations

'What's in the NIDDK CDR?'--public query tools for the NIDDK central data repository

Huaqin Pan et al. Database (Oxford). .

Abstract

The National Institute of Diabetes and Digestive Disease (NIDDK) Central Data Repository (CDR) is a web-enabled resource available to researchers and the general public. The CDR warehouses clinical data and study documentation from NIDDK funded research, including such landmark studies as The Diabetes Control and Complications Trial (DCCT, 1983-93) and the Epidemiology of Diabetes Interventions and Complications (EDIC, 1994-present) follow-up study which has been ongoing for more than 20 years. The CDR also houses data from over 7 million biospecimens representing 2 million subjects. To help users explore the vast amount of data stored in the NIDDK CDR, we developed a suite of search mechanisms called the public query tools (PQTs). Five individual tools are available to search data from multiple perspectives: study search, basic search, ontology search, variable summary and sample by condition. PQT enables users to search for information across studies. Users can search for data such as number of subjects, types of biospecimens and disease outcome variables without prior knowledge of the individual studies. This suite of tools will increase the use and maximize the value of the NIDDK data and biospecimen repositories as important resources for the research community. Database URL: https://www.niddkrepository.org/niddk/home.do.

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Figures

Figure 1
Figure 1
PQT suite of tools at NIDDK CDR website.
Figure 2
Figure 2
CDR PQT suite tables supporting the query tools.
Figure 3
Figure 3
Screenshot showing the predefined categories of ‘Specialty Characteristics’.
Figure 4
Figure 4
Screenshot showing summary statistics of number of subjects for two variables (gender and history of neuropathy) in the EDIC Study in the single study view.
Figure 5
Figure 5
Screenshot showing summary statistics of number of subjects for one variable (history of neuropathy) in two studies (EDIC and GoKinD) in the cross-study view.
Figure 6
Figure 6
Search result of sample types for condition ‘Cirrhosis’.
See this image and copyright information in PMC

References

    1. Cuticchia AJ, Cooley PC, Hall RD, et al. NIDDK data repository: a central collection of clinical trial data. BMC Med. Inform. Decis Mak. 2006;6:19. - PMC - PubMed
    1. Turner CF, Pan H, Silk GW, et al. The NIDDK Central Repository at 8 years—ambition, revision, use and impact. Database. 2011 2011, article ID bar043; doi:10.1093/database/bar043. - PMC - PubMed
    1. Mailman MD, Feolo M, Jin Y, et al. The NCBI dbGaP database of genotypes and phenotypes. Nat. Genet. 2007;39:1181–1186. - PMC - PubMed
    1. BioLINCC in ISBER News. Shea K, Wagner E. BioLINCC: facilitating web access to NHLBI data and biospecimen repositories. 2010;10:5–7. http://www.isber.org/newsletters/documents/July2010.pdf, accessed January 14, 2013.
    1. Massett HA, Atkinson NL, Weber D, et al. Assessing the need for a standardized cancer HUman Biobank (caHUB): findings from a national survey with cancer researchers. J. Natl Cancer Inst. Monogr. 2011 2011, 8–15. - PubMed

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