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. 2013 Jan 31;18(5):20394.
doi: 10.2807/ese.18.05.20394-en.

Interim estimates of influenza vaccine effectiveness in 2012/13 from Canada's sentinel surveillance network, January 2013

D M Skowronski  1 , N Z Janjua, G De Serres, J A Dickinson, A-L Winter, S M Mahmud, S Sabaiduc, J B Gubbay, H Charest, M Petric, K Fonseca, P Van Caeseele, T L Kwindt, M Krajden, A Eshaghi, Y Li
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Free article

Interim estimates of influenza vaccine effectiveness in 2012/13 from Canada's sentinel surveillance network, January 2013

D M Skowronski et al. Euro Surveill. .
Free article

Abstract

The 2012/13 influenza season in Canada has been characterised to date by early and moderately severe activity, dominated (90%) by the A(H3N2) subtype. Vaccine effectiveness (VE) was assessed in January 2013 by Canada's sentinel surveillance network using a test-negative case-control design. Interim adjusted-VE against medically attended laboratory-confirmed influenza A(H3N2) infection was 45% (95% CI: 13-66). Influenza A(H3N2) viruses in Canada are similar to the vaccine, based on haemagglutination inhibition; however, antigenic site mutations are described in the haemagglutinin gene.

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