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. 2013:9:74-8.
doi: 10.3762/bjoc.9.9. Epub 2013 Jan 14.

Removal of benzylidene acetal and benzyl ether in carbohydrate derivatives using triethylsilane and Pd/C

Abhishek Santra  1 , Tamashree Ghosh, Anup Kumar Misra
Affiliations

Removal of benzylidene acetal and benzyl ether in carbohydrate derivatives using triethylsilane and Pd/C

Abhishek Santra et al. Beilstein J Org Chem. 2013.

Abstract

Clean deprotection of carbohydrate derivatives containing benzylidene acetals and benzyl ethers was achieved under catalytic transfer hydrogenation conditions by using a combination of triethylsilane and 10% Pd/C in CH(3)OH at room temperature. A variety of carbohydrate diol derivatives were prepared from their benzylidene derivatives in excellent yield.

Keywords: Pd/C; benzylidene; glycoside; transfer hydrogenation; triethylsilane.

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Figures

Scheme 1
Scheme 1
Removal of benzylidene acetal and benzyl ether by using a combination of triethylsilane and 10% Pd/C.
See this image and copyright information in PMC

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