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Review
. 2013 Mar;26(3):415-20.
doi: 10.1016/j.yebeh.2012.12.018. Epub 2013 Feb 9.

Sudden unexpected death in epilepsy: from the lab to the clinic setting

Vera C Terra  1 , Roberta Cysneiros, Esper A Cavalheiro, Fulvio A Scorza
Affiliations
Review

Sudden unexpected death in epilepsy: from the lab to the clinic setting

Vera C Terra et al. Epilepsy Behav. 2013 Mar.

Abstract

Sudden unexpected death in epilepsy (SUDEP) is defined as sudden, unexpected, witnessed or unwitnessed, non-traumatic, and non-drowning death in a patient with epilepsy. Sudden unexpected death in epilepsy is probably the most common cause of epilepsy-related deaths. Many predisposing and initiating factors may coexist and contribute to SUDEP, but the mechanisms are poorly understood. Cardiac and respiratory deregulation seems to have a major role in SUDEP. Here, we review several advances in understanding the mechanisms involved in SUDEP.

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