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. 1990 Apr;99(1):3-10.
doi: 10.1007/BF01737283.

Distribution of non-telomeric sites of the (TTAGGG)n telomeric sequence in vertebrate chromosomes

J Meyne  1 , R J Baker, H H Hobart, T C Hsu, O A Ryder, O G Ward, J E Wiley, D H Wurster-Hill, T L Yates, R K Moyzis
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Distribution of non-telomeric sites of the (TTAGGG)n telomeric sequence in vertebrate chromosomes

J Meyne et al. Chromosoma. 1990 Apr.

Abstract

The intrachromosomal distribution of non-telomeric sites of the (TTAGGG)n telomeric repeat was determined for 100 vertebrate species. The most common non-telomeric location of this sequence was in the pericentric regions of chromosomes. A variety of species showed relatively large amounts of this sequence present within regions of constitutive heterochromatin. We discuss possible relationships between the non-telomeric distribution of the (TTAGGG)n sequence and the process of karyotype evolution, during which these sites may provide potential new telomeres.

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References

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