Comment
doi: 10.1126/scitranslmed.3005579.
Ovarian aging: breaking up is hard to fix
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- PMID: 23408052
- DOI: 10.1126/scitranslmed.3005579
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Comment
Ovarian aging: breaking up is hard to fix
Sci Transl Med.
.
Abstract
Accumulation of double-stranded DNA breaks and inhibition of DNA repair contributes to reproductive aging by diminishing ovarian reserves in mice and women.
Comment on
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Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans.Sci Transl Med. 2013 Feb 13;5(172):172ra21. doi: 10.1126/scitranslmed.3004925. Sci Transl Med. 2013. PMID: 23408054 Free PMC article.
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