Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Feb 18;6(1):6.
doi: 10.1186/1755-7682-6-6.

Pain and quality of life in patients undergoing radiotherapy for spinal metastatic disease treatment

Affiliations

Pain and quality of life in patients undergoing radiotherapy for spinal metastatic disease treatment

Edgar S Valesin Filho et al. Int Arch Med. .

Abstract

Background: Radiotherapy is an important tool in the control of pain in patients with spinal metastatic disease. We aimed to evaluate pain and of quality of life of patients with spinal metastatic disease undergoing radiotherapy with supportive treatment.

Methods: The study enrolled 30 patients. From January 2008 to January 2010, patients selection included those treated with a 20 Gy tumour dose in five fractions. Patients completed the visual analogue scale for pain assessment and the SF-36 questionnaire for quality of life assessment.

Results: The most frequent primary sites were breast, multiple myeloma, prostate and lymphoma. It was found that 14 spinal metastatic disease patients (46.66%) had restricted involvement of three or fewer vertebrae, while 16 patients (53.33%) had cases involving more than three vertebrae. The data from the visual analogue scale evaluation of pain showed that the average initial score was 5.7 points, the value 30 days after the end of radiotherapy was 4.60 points and the average value 6 months after treatment was 4.25 points. Notably, this final value was 25.43% lower than the value from the initial analysis. With regard to the quality of life evaluation, only the values for the functional capability and social aspects categories of the questionnaire showed significant improvement.

Conclusion: Radiotherapy with supportive treatment appears to be an important tool for the treatment of pain in patients with spinal metastatic disease.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Distribution of the primary sites of metastases.
Figure 2
Figure 2
Average pain score according to the VAS.
Figure 3
Figure 3
Variation in the area of functional capacity using the SF-36.
Figure 4
Figure 4
Variation in the area of social aspects using the SF-36.

References

    1. Loblaw DA, Laperriere NJ, Mackillop WJ. A population-based study of malignant spinal cord compression in Ontario. Clin Oncol (R Coll Radiol) 2003;15:211–217. doi: 10.1016/S0936-6555(02)00400-4. - DOI - PubMed
    1. Conway R, Graham J, Kidd J, Levack P. Scottish Cord Compression Group. What happens to people after malignant cord compression? Survival, function, quality of life, emotional well-being and place of care 1 month after diagnosis. lin Oncol (R Coll Radiol) 2007;19:56–62. doi: 10.1016/j.clon.2006.11.010. - DOI - PubMed
    1. Abbas H, Elyamany A, Salem M, Salem A, Binziad S, Gamal B. The optimal sequence of radiotherapy and chemotherapy in adjuvant treatment of breast cancer. Int Arch Med. 2011;4:35. doi: 10.1186/1755-7682-4-35. - DOI - PMC - PubMed
    1. Rades D, Stalpers LJ, Veninga T, Schulte R, Hoskin PJ, Obralic N, Bajrovic A, Rudat V, Schwarz R, Hulshof MC, Poortmans P, Schild SE. Evaluation of five radiation schedules and prognostic factors for metastatic spinalcord compression. J Clin Oncol. 2005;23:3366–3375. doi: 10.1200/JCO.2005.04.754. - DOI - PubMed
    1. Maximous DW, Abdel-Wanis ME, El-Sayed MI, Abd-Elsayed AA. Preoperative gemcitabine based chemo-radiotherapy in locally advanced non metastatic pancreatic adenocarcinoma. Int Arch Med. 2009;2:7. doi: 10.1186/1755-7682-2-7. - DOI - PMC - PubMed

LinkOut - more resources