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Practice Guideline
. 2013 Apr;93(4):324-5.
doi: 10.1038/clpt.2013.4. Epub 2013 Jan 17.

Clinical pharmacogenetics implementation consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing: 2013 update

M V Relling  1 , E E Gardner, W J Sandborn, K Schmiegelow, C-H Pui, S W Yee, C M Stein, M Carrillo, W E Evans, J K Hicks, M Schwab, T E Klein; Clinical Pharmacogenetics Implementation Consortium
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Practice Guideline

Clinical pharmacogenetics implementation consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing: 2013 update

M V Relling et al. Clin Pharmacol Ther. 2013 Apr.
No abstract available

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References

    1. Relling M.V., Klein T.E. CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network. Clin. Pharmacol. Ther. 2011;89:464–467. - PMC - PubMed
    1. Relling M.V., et al. Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing. Clin. Pharmacol. Ther. 2011;89:387–391. - PMC - PubMed
    1. Krynetski E., Evans W.E. Drug methylation in cancer therapy: lessons from the TPMT polymorphism. Oncogene. 2003;22:7403–7413. - PubMed
    1. González-Lama Y., et al. Thiopurine methyl-transferase activity and azathioprine metabolite concentrations do not predict clinical outcome in thiopurine-treated inflammatory bowel disease patients. Aliment. Pharmacol. Ther. 2011;34:544–554. - PubMed
    1. Adam de Beaumais T., et al. Determinants of mercaptopurine toxicity in paediatric acute lymphoblastic leukemia maintenance therapy. Br J Clin Pharmacol. 2011;71:575–584. - PMC - PubMed

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