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Comment
. 2013;11(2):e1001480.
doi: 10.1371/journal.pbio.1001480. Epub 2013 Feb 12.

A little switch: alternative domain conformations control bacterial flagella rotation direction

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Comment

A little switch: alternative domain conformations control bacterial flagella rotation direction

Richard Robinson. PLoS Biol. 2013.
No abstract available

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Conflict of interest statement

The author has declared that no competing interests exist.

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HAMP domains of bacterial chemoreceptors (MCPs) switch from one conformation (HAMP1) to another (HAMP2) to relay the binding of signaling molecules outside the cell (top) to regulatory circuits within the cell (bottom), thereby flipping the direction of flagellar rotation. HAMP1 and the bacterial cell tumbles; HAMP2 and it runs.
Image credit: Joe Jones.

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