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. 2013;11(2):e1001481.
doi: 10.1371/journal.pbio.1001481. Epub 2013 Feb 12.

Whole animal experiments should be more like human randomized controlled trials

Beverly S Muhlhausler  1 , Frank H Bloomfield, Matthew W Gillman
Affiliations

Whole animal experiments should be more like human randomized controlled trials

Beverly S Muhlhausler et al. PLoS Biol. 2013.

Abstract

The quality of reporting of animal studies lags behind that of human randomized controlled trials but a series of additions to the ARRIVE guidelines will help ensure that the standards are comparable.

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Conflict of interest statement

The authors have declared that no competing interests exist.

References

    1. Altman DG (1996) Better reporting of randomised controlled trials: the CONSORT statement. BMJ 313: 570–571. - PMC - PubMed
    1. Kane RL, Wang J, Garrard J (2007) Reporting in randomized clinical trials improved after adoption of the CONSORT statement. J Clin Epidemiol 60: 241–249. - PubMed
    1. Plint AC, Moher D, Morrison A, Schulz K, Altman DG, et al. (2006) Does the CONSORT checklist improve the quality of reports of randomised controlled trials? A systematic review. Med J Aust 185: 263–267. - PubMed
    1. Kilkenny C, Browne WJ, Cuthill IC, Emerson M, Altman DG (2010) Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. PLoS Biol 8: e1000412 doi:10.1371/journal.pbio.1000412. - DOI - PMC - PubMed
    1. Kilkenny C, Parsons N, Kadyszewski E, Festing MFW, Cuthill IC, et al. (2009) Survey of the quality of experimental design, statistical analysis and reporting of research using animals. PLoS ONE 4: e7824 doi:10.1371/journal.pone.0007824. - DOI - PMC - PubMed

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