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. 2013 Mar;5(3):978-982.
doi: 10.3892/ol.2013.1115. Epub 2013 Jan 8.

Five-point scoring system based on clinicopathological data: A convenient criterion to determine prognosis of patients with colorectal carcinoma

Tadahiro Nozoe  1 , Mayuko Kohno, Tomohiro Iguchi, Takashi Maeda, Takahiro Ezaki
Affiliations

Five-point scoring system based on clinicopathological data: A convenient criterion to determine prognosis of patients with colorectal carcinoma

Tadahiro Nozoe et al. Oncol Lett. 2013 Mar.

Abstract

The aim of this study was to elucidate the significance of a novel staging criterion, a five-point scoring system (FPSS), determined by five histopathological factors of colorectal carcinoma. These factors included depth of invasion, lymph node metastasis, lymphatic invasion, venous invasion and histopathological tumor type. In total, 357 patients with colorectal carcinoma who had had been treated by surgical resection were investigated. One point was assigned to each of the five aforementioned tumor-related pathological factors. The FPSS score was determined by an aggregate of the points. A significant difference was observed between the survival of patients with FPSS scores of 0 and 1, and 2 and 3 (P=0.0002); and FPSS scores of 2 and 3, and 4 and 5 (P<0.0001). We demonstrate that the FPSS is a convenient criterion for stratifying the prognosis of patients with colorectal carcinoma.

Keywords: colorectal carcinoma; five-point scoring system (FPSS); histopathologic feature.

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Figures

Figure 1
Figure 1
Survival curves. Dotted line, FPSS scores of 0 and 1; thin line, FPSS scores of 2 and 3; thick line, FPSS scores of 4 and 5. FPSS; five-point scoring system.
Figure 2
Figure 2
Survival curves for patients who had been treated with curative resection. Dotted line, FPSS scores of 0 and 1; thin line, FPSS scores of 2 and 3; thick line, FPSS scores of 4 and 5. FPSS; five-point scoring system.
See this image and copyright information in PMC

References

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