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. 2013 Oct;68(10):971-3.
doi: 10.1136/thoraxjnl-2012-203201. Epub 2013 Feb 21.

Research in progress: put the orphanage out of business

Andrew Bush  1 , Gisela Anthony, Angelo Barbato, Steve Cunningham, Annick Clement, R Epaud, Carlee Gilbert, Lutz Goldbeck, Kai Kronfeld, Andrew G Nicholson, Nicolaus Schwerk, Matthias Griese; ch-ILD collaborators
Affiliations

Research in progress: put the orphanage out of business

Andrew Bush et al. Thorax. 2013 Oct.

Abstract

Paediatric interstitial lung disease (ILD) is rare and diverse, meaning no single centre will see sufficient children to perform the studies needed to make progress. This EU FP-7 grant will standardise the evaluation of these rare conditions by establishing pan-European multidisciplinary expert panels and establish consensus on treatment protocols and standard operating procedures across Europe. We will work with patient groups to determine optimal treatment end-points and biomarkers. A biobank will be established as a Europe-wide resource for mechanistic studies. Ultimately we aim to do the first randomised controlled trial of a pharmacological treatment in paediatric ILD.

Keywords: ABCA3; Allergic Alveolitis; NEHI; PIG; Paediatric interstitial lung disease; Pulmonary vasculitis; Surfactant protein.

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