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Comment
. 2013 Feb 21;38(2):201-2.
doi: 10.1016/j.immuni.2013.02.005.

Mitochondrial ROS fire up T cell activation

Michael P Murphy  1 , Richard M Siegel
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Free article
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Mitochondrial ROS fire up T cell activation

Michael P Murphy et al. Immunity. .
Free article

Abstract

Metabolic reprogramming has emerged as an important feature of immune cell activation. Two new studies, including Sena et al. (2013) in this issue of Immunity, identify mitochondrial reactive oxygen species (ROS) arising from metabolic reprogramming as signaling molecules in T cell activation.

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