One bug or another: promiscuous T cells form lifelong memory
- PMID: 23438820
- DOI: 10.1016/j.immuni.2013.02.002
One bug or another: promiscuous T cells form lifelong memory
Abstract
As humans age, their T cell repertoire becomes dominated by cells exhibiting "memory" characteristics. In this issue of Immunity, Su et al. (2013) demonstrate that a large percentage of virus-specific CD4(+) T cells also exhibit a memory phenotype in unexposed adults.
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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Virus-specific CD4(+) memory-phenotype T cells are abundant in unexposed adults.Immunity. 2013 Feb 21;38(2):373-83. doi: 10.1016/j.immuni.2012.10.021. Epub 2013 Feb 7. Immunity. 2013. PMID: 23395677 Free PMC article.
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