Response to Sul and Eskin

Comment

Alkes L Price et al. Nat Rev Genet. 2013 Apr.

. 2013 Apr;14(4):300.

doi: 10.1038/nrg2813-c2. Epub 2013 Feb 26.

No abstract available

Comment on

New approaches to population stratification in genome-wide association studies.
Price AL, Zaitlen NA, Reich D, Patterson N. Price AL, et al. Nat Rev Genet. 2010 Jul;11(7):459-63. doi: 10.1038/nrg2813. Nat Rev Genet. 2010. PMID: 20548291 Free PMC article. Review.
Mixed models can correct for population structure for genomic regions under selection.
Sul JH, Eskin E. Sul JH, et al. Nat Rev Genet. 2013 Apr;14(4):300. doi: 10.1038/nrg2813-c1. Epub 2013 Feb 26. Nat Rev Genet. 2013. PMID: 23438871 No abstract available.

1. Price AL, Zaitlen NA, Reich D, Patterson N. New approaches to population stratification in genome-wide association studies. Nat Rev Genet. 2010;11:459–63. - PMC - PubMed
1. Kang HM, Sul JH, Service SK, Zaitlen NA, Kong SY, Freimer NB, Sabatti C, Eskin E. Variance component model to account for sample structure in genome-wide association studies. Nat Genet. 2010;42:348–54. - PMC - PubMed
1. Zhang Z, Ersoz E, Lai CQ, Todhunter RJ, Tiwari HK, Gore MA, Bradbury PJ, Yu J, Arnett DK, Ordovas JM, Buckler ES. Mixed linear model approach adapted for genome-wide association studies. Nat Genet. 2010;42:355–60. - PMC - PubMed
1. Sul JH, Eskin E. Mixed models can correct for population structure for genomic regions under selection. Nat Rev Genet. in press. - PubMed
1. Yang WY, Novembre J, Eskin E, Halperin E. A model-based approach for analysis of spatial structure in genetic data. Nat Genet. 2012;44:725–31. - PMC - PubMed