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Comparative Study
. 2013 Dec;18(12):1247-8.
doi: 10.1038/mp.2013.22. Epub 2013 Feb 26.

Differential engagement of the fronto-limbic network during emotion processing distinguishes bipolar and borderline personality disorder

G S Malhi  1 , M Tanious, K Fritz, C M Coulston, D M Bargh, K L Phan, V Calhoun, P Das
Affiliations
Comparative Study

Differential engagement of the fronto-limbic network during emotion processing distinguishes bipolar and borderline personality disorder

G S Malhi et al. Mol Psychiatry. 2013 Dec.
No abstract available

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Conflict of interest statement

Conflict of interest

MT, KF, CC, DB, KLP, and PD have no conflicts of interest to report.

Figures

Figure 1
Figure 1. (a): Schematic of neuroimaging activations and (b) correlation of lateral PFC activations with DERS
(a) Schematic of neuroimaging activations. This figure shows the patterns of activation in patients compared to HC. Purple is used to depict a similar direction of activity in patient groups. Specifically, dl-PFC activation was decreased whereas vl-PFC activation was increased in both BD and BPD. Green is used to depict activations in opposing directions in patient groups. Specifically, dm-PFC activation was increased in BD, while Ag activity was decreased in BPD. (b) Correlation of lateral PFC activations with DERS. In all subjects, BOLD activity in the lateral PFC correlated with DERS Total scores. Increased vl-PFC activity and decreased dl-PFC activity in our patients, indicates greater difficulties in regulating emotion.
See this image and copyright information in PMC

References

    1. Coulston C, Tanious M, Mulder RT, Porter RJ, Malhi GS. Aust N Z J Psychiatry - PubMed
    1. Ochsner KN, Ray RR, Hughes B, McRae K, Cooper JC, Weber J, et al. Psychol Sci. 2009;20:1322–1331. - PMC - PubMed
    1. Phillips ML, Ladouceur CD, Drevets WC. Mol Psychiatry. 2008;13:833–857. - PMC - PubMed
    1. Ruocco AC, Amirthavasagam S, Choi-Kain LW, McMain SF. Biol Psychiatry - PubMed
    1. Malhi GS, Lagopoulos J, Owen AM, Ivanovski B, Shnier R, Sachdev P. J Affect Disord. 2007;97:109–122. - PubMed