Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1975 Feb;28(2):132-5.
doi: 10.7164/antibiotics.28.132.

Stability studies with amphotericin B and amphotericin B methyl ester

D P Bonner, W Mechlinski, C P Schaffner
Free article
Comparative Study

Stability studies with amphotericin B and amphotericin B methyl ester

D P Bonner et al. J Antibiot (Tokyo). 1975 Feb.
Free article

Abstract

In solid form, amphotericin B and amphotericin B methyl ester free base exhibit similar stability. Acid salts of the methyl ester derivative stored under identical conditions are less stable. In solution, amphotericin B is generally more stable than its methy ester salts. However, when pH is adjusted to 6.0 and storage temperature held at 5 degrees C the methyl ester salts reflect the stability exhibited by the parent compound, amphotericin B.

PubMed Disclaimer

Publication types