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Clinical Trial
. 1990 Apr;34(4):610-3.
doi: 10.1128/AAC.34.4.610.

Efficacy and safety of mercuric oxide in the treatment of bacterial blepharitis

R A Hyndiuk  1 , E M Burd, A Hartz
Affiliations
Clinical Trial

Efficacy and safety of mercuric oxide in the treatment of bacterial blepharitis

R A Hyndiuk et al. Antimicrob Agents Chemother. 1990 Apr.

Abstract

A double-masked, placebo-controlled, randomized study was done to assess the safety and clinical and quantitative microbiologic efficacy of 1% mercuric oxide (yellow) ophthalmic ointment in the treatment of eyelid infections, i.e., bacterial blepharitis. A total of 39 patients with bacterial counts and clinical signs indicative of eyelid infection were treated twice daily for 7 days. Clinical biomicroscopic examination and quantitative microbiologic cultures were done just prior to initiation of treatment and again on days 3 and 7. Statistical analysis revealed a significant improvement in the clinical signs, bacterial count, cure rate, and improvement rate for subjects taking the active medication, compared with those taking the placebo on days 3 and 7. In addition, the medication was well tolerated.

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References

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