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Comparative Study
. 2014 Apr;24(2):174-8.
doi: 10.1055/s-0033-1333634. Epub 2013 Feb 26.

Surgical stress after open and transumbilical laparoscopic-assisted appendectomy in children

Angela Simona Montalto, Pietro Impellizzeri, Maria Grasso  1 , Pietro Antonuccio  2 , Caterina Crisafi  3 , Gianfranco Scalfari  2 , Francesco Arena  2 , Carmelo Salpietro  1 , Mario Lima  4 , Carmelo Romeo  2
Affiliations
Comparative Study

Surgical stress after open and transumbilical laparoscopic-assisted appendectomy in children

Angela Simona Montalto et al. Eur J Pediatr Surg. 2014 Apr.

Erratum in

  • Eur J Pediatr Surg. 2014 Apr;24(2):e1. Simona, Angela [corrected to Montalto, Angela Simona]

Abstract

Introduction: The transumbilical laparoscopic-assisted appendectomy (TULAA) effects on the surgical stress response in children have not been studied. Our aim is to investigate the stress response in TULAA.

Methods: A total of 35 children underwent the appendectomy by open approach (OA) or TULAA approach. Interleukins (ILs)-6, -18, and -10 were measured before (T0), at the beginning (T1a), and at the end of surgery (T1b) and 24 hours after (T2).

Results: An increase in IL-6 levels at T1b and T2 and in IL-18 at T2 was observed after OA. A significant increase of both IL-6 and IL-18 were observed at T2 but values were less compared with OA (11.6 ± 4.4 vs. 31.9 ± 8.9 pg/mL for IL-6, p = 0.0006; 145.6 vs. 174.9 pg/mL for IL-18, p = NS).

Conclusions: A significant reduction in the postoperative cytokines in TULAA group suggests that this approach causes less surgical trauma in children.

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