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Comment
. 2013 Mar;83(3):348-50.
doi: 10.1038/ki.2012.454.

IgG4: a tantalizing link between causes of membranous glomerulonephritis and systemic disease

John H Stone  1
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Free article
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IgG4: a tantalizing link between causes of membranous glomerulonephritis and systemic disease

John H Stone. Kidney Int. 2013 Mar.
Free article

Abstract

Alexander et al. give a detailed description of IgG4-related membranous glomerulonephritis (MGN). Their data delineate for the first time in IgG4-related disease (IgG4-RD) a second pattern of tissue injury occurring within the same organ. The paper highlights that MGN can occur alone or simultaneously with IgG4-related tubulointerstitial nephritis. Thus, it extends our understanding of IgG4-RD and illuminates potential pathways for new investigations into its pathophysiology.

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