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Comment
. 2013 Feb 25;24(4):340-1.
doi: 10.1016/j.devcel.2013.02.003.

Nerve control of blood vessel patterning

Takako Makita  1
Affiliations
Comment

Nerve control of blood vessel patterning

Takako Makita. Dev Cell. .

Abstract

Patterning of embryonic blood vessels occurs in association with nerves. In this issue of Developmental Cell, Li et al. (2013) report that nerve-derived chemokine Cxcl12 (also known as SDF-1), acting through its receptor Cxcr4, initiates blood vessel remodeling along cutaneous nerve trajectories to establish the proper pattern of cutaneous arteries.

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Figures

Figure 1
Figure 1. Developmental and Mature Organization of Cutaneous Blood Vessels and Nerves
Schematic illustrations of the sources of cutaneous (DRG sensory and spinal motor) and sympathetic nerves during development at the time of their initial association with major blood vessels that supply the limb skin (left) and the mature organization of cutaneous blood vessels and nerve endings of the skin (right).
See this image and copyright information in PMC

Comment on

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