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Comment
. 2013 Mar 1;339(6123):1044-5.
doi: 10.1126/science.1236226.

Immunology. Welcome to the microgenderome

Magdalena B Flak  1 , Joana F Neves, Richard S Blumberg
Affiliations
Comment

Immunology. Welcome to the microgenderome

Magdalena B Flak et al. Science. .

Abstract

Commensal gut bacteria reinforce the gender bias observed in an autoimmune form of diabetes.

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Figure
Figure. Gender, microbes, and disease
Male puberty (in mice; not shown) leads to changes in the gut microbiota that reinforce testosterone production, which is protective against the development of T and B cell functions linked to autoimmune disease. In mice, the protective properties of the male-associated microbiota can be transferred to younger females and confer testosterone-mediated protection from autoimmune disease upon the recipients.
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